Presentation

100mL of aqueous iodine solution at 2% molecular iodine (I₂) and 4% potassium iodide (KI).

Information

About Lugol's solution

Developed in 1829 by the French physician Jean Guillaume Auguste Lugol at the Saint-Louis Hospital in Paris, Lugol's solution (Solutio Lugoli) combines two forms of iodine: molecular iodine (I₂), which is barely soluble in water, and potassium iodide (KI), which dissolves it by forming triiodide ions (I₃⁻).

Still used in medicine, dentistry and laboratories (starch staining), it is offered here at 2% molecular iodine, a more dilute concentration than ‘strong’ 5% Lugol's.

Composition per 100mL

This amounts to about 2.5mg of iodine per drop. For comparison, the nutrient reference value (NRV) for iodine is 150µg per day: this solution is therefore not a food supplement.

Traditional uses and dosage

The dosage depends on the intended use. Do not combine several uses without professional advice.

Internal use (oral route), on medical advice only: generally 1 drop per day, diluted in a large glass of water or juice, taken with a meal and never on an empty stomach. The dose and duration are set by the doctor; prolonged use requires thyroid monitoring (TSH, free T4).

External use: apply undiluted, locally with a cotton swab or compress, to small superficial wounds, 1 to 2 times a day. Do not apply to large areas. Avoid contact with the eyes, mucous membranes and clothing (persistent stains). Before first use, test on a small area of skin.

Mouth rinse: dilute 5 to 10 drops in a glass of lukewarm water, rinse for 30 to 60 seconds, then spit out without swallowing. 1 to 2 times a day, for 3 to 5 days at most.

Precautions for use

Medical or pharmaceutical advice is essential before any oral use. Never exceed the indicated doses.

Do not use in case of hypersensitivity to iodine or to any of the components; thyroid disease (hyperthyroidism, Graves' disease, nodules, Hashimoto's thyroiditis) or a history of thyroid cancer; pregnancy or breastfeeding; dermatitis herpetiformis; severe kidney failure. In children under 12: on medical advice only.

Ask your doctor or pharmacist for advice if you are taking antithyroid drugs, amiodarone, lithium, potassium salts or potassium-sparing diuretics, and before any examination with iodinated contrast media or a thyroid scan.

Possible side effects: temporary brown staining of the skin, metallic taste, digestive discomfort (especially on an empty stomach), local irritation or allergic reaction. Excess iodine may show as a runny nose, watery eyes, excessive salivation, headache or an acne-like rash: stop use and consult a doctor.

In case of accidental ingestion or overdose, contact a poison centre immediately: Belgium 070 245 245; Luxembourg 8002 5500; France +33 1 40 05 48 48 (Paris poison centre).

Storage

Store at room temperature (< 25°C), away from light, with the bottle tightly closed. Do not expose to heat or frost. Keep out of the reach and sight of children.

Do not use after the expiry date shown on the bottle, or if the colour, appearance or odour changes.

Important: this magistral preparation is neither a medicinal product with a marketing authorisation (MA) nor a food supplement. Prepared in a pharmacy according to good preparation practices, it must be used under the supervision of a healthcare professional.

Quantity:

100mL (amber glass bottle with dropper)

Compounding pharmacy:

MULTIPHARMA MOSSOUX PHILIPPE

Responsible pharmacist: Philippe MOSSOUX

Boulevard Jean de Wilde 4

4000 Liège

BELGIUM